履历

• 球友会博士（2015）
• 球友会教授（2023-）\博导（2023-）
• 海洋生物制药国家地方联合工程研究中心（大连）主任（2020-）
• 海洋食品精深加工关键技术省部共建协同创新中心（球友会）主任（2020-）
• 球友会七鳃鳗研究中心主任（2020-）

研究方向

代表性论文

• Yuesi Zhou, Zihao Yan 2, Ya Pang, Yao Jiang, Ruyu Zhuang, Shuyuan Zhang, Ayqeqan Nurmamat,Min Xiu, Ding Li, Liang Zhao,Xin Liu, Qingwei Li, and Yinglun Han.Exploring the Multiple Roles of Notch1 in BiologicalDevelopment: An Analysis and Study Based onPhylogeneticsand Transcriptomics.Int. J. Mol. Sci. 2024, 25, 611.(通讯作者)
•  Ruyu Zhuang, Zihao Yan, Yicheng Gao, Ayqeqan Nurmamat, Shuyuan Zhang, Min Xiu, Yuesi Zhou, Ya Pang, Ding Li, Liang Zhao, Xin Liu, Yinglun Han. Evolutionary and functional analysis of metabotropic glutamate receptors in lampreys. Fish Physiol Biochem https://doi.org/10.1007/s10695-024-01374-x. (通讯作者)
• Ting Zhu, Yongxin Li, Yue Pang, Yinglun Han, Jun Li, Zhongkai Wang, Xin Liu, Haorong Li, Yishan Hua, Hui Jiang, Hongming Teng, Jian Quan, Yu Liu, Ming Geng, Meiao Li, Fan Hui, Jinzhao Liu, Qiang Qiu, Qingwei Li,and Yandong Ren. Chromosome-level genome assembly of Lethenteron reissneri provides insights into lamprey evolution. Mol Ecol Resour. 2021 Feb;21(2):448-463.  (共同第一作者)
• Yue Pang, Meng Gou, Kai Yang, Jiali Lu, Yinglun Han , Hongming Teng, Changzhi Li, Haina Wang, Caigang Liu , Kejia Zhang, Yongliang Yang, Qingwei Li. Crystal structure of a cytocidal protein from lamprey and its mechanism of action in the selective killing of cancer cells. Cell Commun Signal. 2019 May 27;17(1):54.   (共同第一作者)
• Qing Han,Yinglun Han,Hongyan Wen,Yue Pang and Qingwei Li. Molecular Evolution of Apolipoprotein Multigene Family and the Original Functional Properties of Serum Apolipoprotein (LAL2) in Lampetra japonica Front Immunol 2020 Aug 11;11:1751.(共同第一作者)
• Jun Li, Qinghua Ma, Huaixiu Liu, Xiaoping Song, Yue Pang, Peng Su, Feng Sun, Meng Gou, Jingjing Lu, Yue Shan, Xin Liu, Qingwei Li, Yinglun Han. Complement component C1q plays a critical role in VLRA/VLRC-mediated.immune response. Dev Comp Immunol. 2020 Oct;111:103750. (通讯作者)
• Yinglun Han,Jun Li,Yue Pang,Lei Xu,Qinghua Ma,Huaixiu Liu,Xiaoping Song,Peng Sua,Feng Suna,Meng Gou,Jingjing Lua,Yue Shana,Xin Liu, Qingwei Li. Lamprey VLRB participates in pathogen detection, VLRB/L-BLNK/L-NF-κB (B-like cells) signal transduction, and development. Fish Shellfish Immunol. 2020 Oct;105:446-456.
• Jun Li, Qinghua Ma, Huaixiu Liu, Xiaoping Song, Yue Pang, Peng Su, Feng Sun, Meng Gou, Jingjing Lu, Yue Shan, Xin Liu, Qingwei Li, Yinglun Han. VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii.  Fish Shellfish Immunol. 2020 Nov;106:307-317.(通讯作者)
• Yinglun Han, Xin Liu , Biyue Shi , Rong Xiao , Meng Gou , Hao Wang, Qingwei Li. Identification and characterisation of the immune response properties of Lampetra japonica BLNK. Sci Rep. 2016 Apr 29;6:25308.
• Jun Li, Yinglun Han, Ting Zhu , Yue Pang, Qingwei Li. Immune-related gene expression in the early development of lamprey larva. Acta Biochim Biophys Sin (Shanghai). 2018 Sep 1;50(9):938-940.(共同第一作者)

开设课程

• 人体病理学（本科）
• 现代生物学研究进展、动物学（研究生）

科研课题

• 国家自然科学基金面上项目：揭开B细胞淋巴瘤“神秘面纱”——七鳃鳗胞苷脱氨酶介导可变淋巴细胞受体装配机制研究，起止时间：2023.01-2026.12,54万元，主持；
• 国家自然科学基金青年项目：七鳃鳗一种新型模式识别蛋白LIP识别病原菌激活VLRB+类淋巴细胞的分子机制研究，起止时间：2017.01-2019.12,20万元，主持；
• 辽宁省“兴辽英才计划”青年拔尖项目：七鳃鳗胞苷脱氨酶介导VLRs类别转换重组机制研究，起止时间：2021.01-2023.12，50万元，主持；
• 辽宁省自然科学基金面上项目：七鳃鳗可变淋巴受体B介导B细胞样信号转导机制研究，起止时间：2020.01-2022.12，5万元，主持；
• 大连市科技人才创新支持计划-杰出青年科技人才项目：基于海洋生物候选药物-七鳃鳗胞苷脱氨酶建立针对B细胞淋巴瘤早期精准诊断技术，起止时间：2023.11-2026.10,100万元，主持。